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ATP Citrate Lyase Mouse anti-Human, Clone: 3A10, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Thermo Scientific MA532947

Catalog No. PIMA532947


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Description

Description

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
Specifications

Specifications

ATP Citrate Lyase
Monoclonal
Unconjugated
ACLY
Liquid
ACLY
Synthetic peptide, corresponding to amino acids C-terminus of Human ATP-Citrate Lyase.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
3A10
0.1M tris glycine with 50% glycerol and 0.02% sodium azide; pH 7.2
P53396
ATP-citrate synthase; ATP-citrate (pro-S-)-lyase; ACL; Citrate cleavage enzyme; ACLY
Mouse
IgG2a
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
47
SDS
Documents
Product Certifications
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