ATP Citrate Lyase Mouse anti-Human, Clone: OTI3G8, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525067
DescriptionATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
|ATP Citrate Lyase|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|ACL, ATPCL, CLATP, ATP citrate synthase, ATP-citrate (pro-S-)-lyase, ATP-citrate synthase, citrate cleavage enzyme|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of ACLY produced in HEK293T cell|
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