ATP Synthase gamma Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA590325

Catalog No. PIPA590325

Description

Immunogen sequence: ATLKDITRRL KSIKNIQKIT KSMKMVAAAK YARAERELKP ARIYGLGSLA LYEKADIKGP EDKKKHLLIG VSSDRGLCGA IHSSIAKQMK SEVATLTAAG KEVMLVGIGD KIRGILYRTH SDQFLVAFKE VGRKPPTFGD ASVIALELLN SGYEFDEGSI IFNKFRSVIS YKTEEKPIFS LNTVASADSM SIYDDIDADV LQNYQEYNLA NIIYYSLKES TTSEQSARMT AMDNASKNAS EMIDKLTLTF NRTRQAVITK ELIEIISGAA ALD; Positive Samples: LO2, U-87MG, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Rat brain, Rat liver; Cellular Location: Mitochondrion, Mitochondrion inner membrane, Peripheral membrane protein

This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14.

Specifications

• Antigen: ATP Synthase gamma
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP5F1C
• Gene Alias: 1700094F02Rik, ATP synthase F1 subunit gamma, ATP synthase gamma chain, mitochondrial, ATP synthase gamma-subunit gene encoding a mitochondrial protein, ATP synthase subunit gamma, mitochondrial, ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1, ATP5C, Atp5c1, ATP5CL1, ATP5F1C, F1 gamma, F-ATPase gamma subunit, mitochondrial ATP synthase, gamma subunit 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116550, 11949, 509
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
• Gene Accession No.: P35435, P36542, Q91VR2
• Gene Symbols: ATP5F1C
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-298 of human ATP5C1 (NP_0010019731)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG