Invitrogen™ ATP11B Monoclonal Antibody (4H8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA521425

Catalog No. PIMA521425

Description

Peptide Sequence: DIIKKVFDRH LHPTSTEKAQ LTETNAGIKC LDSMCCFPEG EAACASVGRM LERVIGRCSP THISRSWSAS DPFYTNDRSI LTLSTMDSST C.

ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.

Specifications

• Antigen: ATP11B
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: Q9Y2G3
• Gene Symbols: ATP11B
• Immunogen: ATP11B (NP_055431, 1087 a.a. ~ 1177 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: ELISA, Western Blot
• Clone: 4H8
• Conjugate: Unconjugated
• Gene: ATP11B
• Gene Alias: 1110019I14Rik; ATP11B; ATPase class VI type 11B; ATPase IR; ATPase phospholipid transporting 11B (putative); ATPase, class VI, type 11B; ATPIF; ATPIR; KIAA0956; mKIAA0956; P4-ATPase flippase complex alpha subunit ATP11B; Probable phospholipid-transporting ATPase IF; TIEG; TIEG1; truncated ATPase 11B protein
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23200
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid