ATP13A2 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA116975

Catalog No. 01-670-152

Description

Suggested positive control: human and mouse brain membrane prep lysate.

Neurodegenerative disorders such as Parkinson and Alzheimer disease cause motor and cognitive dysfunction and belong to a heterogeneous group of common and disabling disorders. ATP13A2, otherwise known as PARK9, is a neuronal P-type ATPase gene underlying an autosomal recessive form of early-onset parkinsonism with pyramidal degeneration and dementia. ATP13A2 protein is located in the membrane of these lysosomes and is formed most strongly in the brain, especially in the substantia nigra, a brain region which is known to play a central role in Parkinson's disease.

Specifications

• Antigen: ATP13A2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ATP13A2
• Gene Alias: 1110012E06Rik; AA589443; AT132 antibody; Atp13a2; ATPase 13A2; ATPase type 13A2; Cation-transporting ATPase 13A2; CLN12; HSA9947; HSA9947 antibody; KRPPD; PARK9; probable cation-transporting ATPase 13A2; putative ATPase; RGD1307977; RP1-37C10.4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23400, 74772
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 0.75 mg/mL
• Formulation: tris glycine with 150mM NaCl and 0.05% sodium azide
• Gene Accession No.: Q9CTG6, Q9NQ11
• Gene Symbols: ATP13A2
• Immunogen: Synthetic peptide corresponding to residues 200-300 of human ATP13A2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG