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ATP6V1B1 Mouse anti-Human, Clone: OTI1H6, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA502677
Description
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c′, c′, and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.Specifications
ATP6V1B1 | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
P15313 | |
ATP6V1B1 | |
Full length human recombit protein of human ATP6V1B1 produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG1 |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI1H6 | |
Unconjugated | |
ATP6V1B1 | |
ATP6B1, RTA1B, VATB, VMA2, VPP3 | |
Mouse | |
Affinity Chromatography | |
RUO | |
525 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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