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ATP6V1B1 Mouse anti-Human, Clone: OTI6D2, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA502519

Catalog No. 50-167-3572



Description

Description

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c ft., c ft., and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.
Specifications

Specifications

ATP6V1B1
Monoclonal
0.73 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P15313
ATP6B1, RTA1B, VATB, VMA2, VPP3
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
525
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI6D2
Unconjugated
ATP6V1B1
Liquid
ATP6V1B1
Full length human recombit protein of human ATP6V1B1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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