Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

ATRX Mouse anti-Human, Clone: 60.1, Abnova™

Mouse monoclonal antibody raised against synthetic peptide of human ATRX.

Manufacturer:  Abnova Corporation MAB12915

Catalog No. 89-933-599


Add to cart

Description

Description

The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Specifications

ATRX
60.1
Mouse monoclonal antibody raised against synthetic peptide of human ATRX.
In PBS, pH 7.2.
ATR2/MGC2094/MRXHF1/RAD54/RAD54L/SFM1/SHS/XH2/XNP/ZNF-HX
Mouse
IgG
50 uL
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
ELISA, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Liquid
ATRX
A mixture of synthetic peptides corresponding to residues within 1-300 and 450-741 of human ATRX.
Protein G purification
RUO
Primary
546
SDS
Documents
Product Certifications
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit