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Tocris™ AVE 1625

Potent and selective CB1 receptor antagonist

Manufacturer:  Tocris™ 6763/10

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Catalog No. 67-631-0


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Description

Description

AVE 1625 is a potent and selective CB1 receptor antagonist (IC50 values are 25 and 10 nM for human and rat CB1R, respectively). Exhibits >400-fold selectivity for CB1 over CB2 receptors. Attenuates Olanzapine (Cat. No. 4349) induced weight gain and food intake in rats with no effect on energy expenditure or motility. Also improves cognitive function in rodent schizophrenia models and ameliorates extrapyramidal side-effects of antipsychotics.
Specifications

Specifications

497.38
Potent and selective CB1 receptor antagonist
Drinabant
C23H20Cl2F2N2O2S
98%
10 mg
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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