Tocris™ AVE 1625
Potent and selective CB1 receptor antagonist
Manufacturer: Tocris™ 6763/10
DescriptionAVE 1625 is a potent and selective CB1 receptor antagonist (IC50 values are 25 and 10 nM for human and rat CB1R, respectively). Exhibits >400-fold selectivity for CB1 over CB2 receptors. Attenuates Olanzapine (Cat. No. 4349) induced weight gain and food intake in rats with no effect on energy expenditure or motility. Also improves cognitive function in rodent schizophrenia models and ameliorates extrapyramidal side-effects of antipsychotics.
|Potent and selective CB1 receptor antagonist|
Safety and Handling
Recommended Storage : Store at -20°C
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