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Tocris™ AZ 10417808

Selective non-peptide caspase-3 inhibitor

Manufacturer:  Tocris™ 2172/10

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Catalog No. 21-721-0

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For Research Use Only



Selective non-peptide inhibitor of caspase-3 (Ki = 247nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10µM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC50 = 14.9µM).
  • Chemical Name: 2-[(3,4-Dichlorophenyl)amino]-1,4-dihydro-6-nitro-4-oxo-N-2-propenyl-8-quinazolinecarboxamide
  • Formula: C18H13Cl2N5O4
  • CAS Number: 331645-84-2
  • Solubility: Soluble to 25mM in DMSO
  • Purity: >98
Description & Specifications


AZ 10417808
AZ 10417808
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