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Tocris Bioscience™ AZ 6102

Potent TNKS1/2 inhibitor

$218.50 - $902.00

Specifications

Chemical Name or Material rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
Molecular Formula C25H28N6O
CAS 1645286-75-4
Product Type Target: Tankyrase Inhibitors
Formula Weight 428.53
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
57-751-0 View Documents Tocris Bioscience™
5775/10
10mg Each for $218.50
Add to cart
 
57-755-0 View Documents Tocris Bioscience™
5775/50
50mg Each for $902.00
Add to cart
 
Description

Description

Potent TNKS2 and TNKS1 inhibitor (IC50 values are 1 and 3 nM, respectively). Exhibits >100-fold selectivity for TNKS1/2 over PARP-1, PARP-2 and PARP-6. Inhibits Wnt signaling in DLD-1 cells (IC50 = 5 nM). Exhibits moderate oral bioavailability.
Specifications

Specifications

rel-2-[4-[6-[(3R,5S)-3,5-Dimethyl-1-piperazinyl]-4-methyl-3-pyridinyl]phenyl]-3,7-dihydro-7-methyl-4H-pyrrolo[2,3-d]pyrimidin-4-one
1645286-75-4
428.53
C25H28N6O
Target: Tankyrase Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at −20°C

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