Tocris™ AZD 7762 hydrochloride

Potent and selective ATP-competitive inhibitor of Chk1 and Chk2

Manufacturer: Tocris™ 5199/10

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Catalog No. 51-991-0

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For Research Use Only


    Specifications

    Product Type AZD 7762 hydrochloride
    Inhibitors AZD 7762 hydrochloride
    Purity >98
    Molecular Weight 398.88
    Quantity 10mg

    Potent and selective ATP-competitive inhibitor of Chk1 and Chk2 (IC50 vales are 5nM for both kinases); displays at least >10 fold selectivity over a panel of 164 kinases. Potentiates cytotoxicity of DNA-damaging agents. Active in vivo.

    • Chemical Name: 3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide hydrochloride
    • Formula: C17H19FN4O2S.HCl
    • CAS Number: 1246094-78-9
    • Solubility: Soluble to 100mM in water and to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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