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Tocris Bioscience™ AZD 9272

Potent and selective mGlu5 antagonist; brain penetrant

Supplier:  Tocris Bioscience™ 5613/50

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Catalog No. 56-135-0


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Description

Description

AZD 9272 is a potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.
Specifications

Specifications

3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
50 mg
C14H6F2N4O
>98%
327056-26-8
Group I mGluR Antagonists
284.22
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Safety and Handling

Safety and Handling

Recommended Storage : Store at Room Temperature

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