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Tocris Bioscience™ AZD 9272

Potent and selective mGlu5 antagonist; brain penetrant

$159.80 - $672.50

Specifications

Chemical Name or Material 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
Molecular Formula C14H6F2N4O
CAS 327056-26-8
Product Type Target: Group I mGluR Antagonists
Formula Weight 284.22
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
56-135-0 View Documents Tocris Bioscience™
5613/50
50mg Each for $672.50
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56-131-0 View Documents Tocris Bioscience™
5613/10
10mg Each for $159.80
Add to cart
 
Description

Description

Potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.
Specifications

Specifications

3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile
327056-26-8
284.22
C14H6F2N4O
Target: Group I mGluR Antagonists
Safety and Handling

Safety and Handling

Recommended Storage : Store at RT

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