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Azilsartan, Tocris Bioscience™

Catalog Number p-4816548
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
147403-03-0
C25H20N4O5
456.46
MFCD20278186
KGSXMPPBFPAXLY-UHFFFAOYSA-N
azilsartan, unii-f9nux55p23, azilsartan tak-536, chembl57242, 2-ethoxy-1-2'-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl biphenyl-4-yl methyl-1h-benzimidazole-7-carboxylic acid, 1h-benzimidazole-7-carboxylic acid, 1-2'-2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl 1,1'-biphenyl-4-yl methyl-2-ethoxy, 1-2'-2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl 1,1'-biphenyl-4-yl methyl-2-ethoxy-1h-benzimidazole-7-carboxylic acid, 2-ethoxy-1-2'-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl biphenyl-4-yl methyl-1h-benzo d imidazole-7-carboxylic acid, 2-ethoxy-1-2'-4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl biphenyl-4-yl methyl benzimidazole-7-carboxylic acid, 2-ethoxy-3-4-2-5-oxo-2h-1,2,4-oxadiazol-3-yl phenyl phenyl methyl benzimidazole-4-carboxylic acid
9825285
CHEBI:68850
2-ethoxy-1-{[2'-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
CCOC1=NC2=CC=CC(C(O)=O)=C2N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NC(=O)ON1
This item is not returnable. View return policy
147403-03-0
C25H20N4O5
456.46
MFCD20278186
KGSXMPPBFPAXLY-UHFFFAOYSA-N
azilsartan, unii-f9nux55p23, azilsartan tak-536, chembl57242, 2-ethoxy-1-2'-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl biphenyl-4-yl methyl-1h-benzimidazole-7-carboxylic acid, 1h-benzimidazole-7-carboxylic acid, 1-2'-2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl 1,1'-biphenyl-4-yl methyl-2-ethoxy, 1-2'-2,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl 1,1'-biphenyl-4-yl methyl-2-ethoxy-1h-benzimidazole-7-carboxylic acid, 2-ethoxy-1-2'-5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl biphenyl-4-yl methyl-1h-benzo d imidazole-7-carboxylic acid, 2-ethoxy-1-2'-4,5-dihydro-5-oxo-1,2,4-oxadiazol-3-yl biphenyl-4-yl methyl benzimidazole-7-carboxylic acid, 2-ethoxy-3-4-2-5-oxo-2h-1,2,4-oxadiazol-3-yl phenyl phenyl methyl benzimidazole-4-carboxylic acid
9825285
CHEBI:68850
2-ethoxy-1-{[2'-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl]methyl}-1H-1,3-benzodiazole-7-carboxylic acid
CCOC1=NC2=CC=CC(C(O)=O)=C2N1CC1=CC=C(C=C1)C1=CC=CC=C1C1=NC(=O)ON1

Potent AT1 receptor inverse agonist; antihypertensive

Potent angiotensin II type 1 (AT1) receptor inverse agonist (IC50 = 2.6 nM at the human AT1 receptor). Inhibits angiotensin II-induced IP1 accumulation in COS-7 cells; decreases maximal contraction of rabbit aortic strips in a concentration-dependent manner (pD'2 = 9.9). Antihypertensive; prevents vascular cell proliferation and expression of PAI-1.
Quantity 10 mg
Formula Weight 456.45
Percent Purity >98%
Chemical Name or Material Azilsartan
Recommended Storage Store at Room Temperature
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