B4GALT4 Mouse anti-Human, Clone: OTI8B6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526920
DescriptionThis gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene appears to mainly play a role in glycolipid biosynthesis. Two alternatively spliced transcript variants have been found for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|B4Gal-T4; beta4Gal-T4; UDP-Gal:beta-GlcNAc beta-1; 4-galactosyltransferase 4; UDP-Gal:betaGlcNAc beta 1; 4- galactosyltransferase 4; UDP-galactose:beta-N-acetylglucosamine beta-1; 4-galactosyltransferase 4; beta-1; 4-GalTase 4; beta-1; 4-galactosyltransferase 4; beta-N-acetylglucosaminyl|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 40-322 of B4GALT4 produced in E.coli|
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