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B7-H3 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 144531AP150UL

Encompass_Preferred

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Catalog No. 50-172-9463


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Description

Description

CD276 is a member of the B7 family of co-stimulatory molecules also known as B7-H3. CD276 is a type I transmembrane protein that induces the proliferation of CD4+ and CD8+ T cells, enhances the generation of cytotoxic T cells and selectively stimulates the production of interferon gamma. Expression of CD276 can be induced on dendritic cells and monocytes by inflammatory cytokines, and is also widely expressed in peripheral tissues including the heart, kidney, testis and colon. In humans, CD276 exists as two isoforms which result from gene duplication and differential splicing. CD276 is reported to have therapeutic potential for the regulation of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy.
Specifications

Specifications

B7-H3
Polyclonal
Unconjugated
CD276
4Ig B7 H3, B7 homolog 3, B7-H3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule, UNQ309/PRO352
Rabbit
Antigen Affinity Chromatography
RUO
80381
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.19 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5ZPR3
CD276
B7-H3 Fusion Protein Ag6006
150 μL
Primary
Human
Antibody
IgG
SDS
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