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Human BACE2, Synthetic Peptide, Invitrogen™

Synthetic Peptide

Manufacturer:  Invitrogen PEP0075

Catalog No. PEP0075


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Description

Description

BACE2 Synthetic Peptide, PEP-0075, from Invitrogen.

BACE2 or Beta Secretase 2 is responsible for the proteolytic processing of the amyloid precursor protein (APP). BACE2 cleaves APP between residues 690 and 691. This cleavage leads to the generation and extracellular release of beta-cleaved soluble APP. BACE2 is also know to cleave APP between residues 671 and 672. Accumulation of APP is a signature of Alzheimer disease and frequent complication of adult Down syndrome patients. This peptide corresponds to 16 amino amino terminus of human BACE2.PEP-0075 can be used as a blocking peptide with polyclonal antibody PA5-19950.
Specifications

Specifications

Synthetic Peptide
purified
50μg
Blocking Assay, Control
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Human
RUO
0.02% sodium azide
BACE2
Blocking Assay, Control
25825
Human
200μg/mL
Liquid
N
PBS
-20°C
Human BACE2
Q9Y5Z0
Peptide
Documents
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