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Tocris Bioscience™ BAG 956
Dual PI 3-kinase and PDPK1 (PDK1) inhibitor
Supplier: Tocris Bioscience™ 3606/50
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Description
BAG 956 is a dual PDPK1 (PDK1) and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDPK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively). Inhibits cellular AKT phosphorylation at Thr308. Blocks cell proliferation, causing arrest in G1 phase of the cell cycle. Slows tumor progression in mouse xenograft models.Specifications
| 98% | |
| 50 mg | |
| 427.5 |
| Store at -20°C | |
| BAG 956 | |
| BAG 956 |
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