Invitrogen™ BAG5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118905

Catalog No. PIPA5118905

Description

Antibody detects endogenous levels of total BAGE5.

It has been hypothesizes that the BAG-5 protein will induce the death of nigral neurons through its predicted interaction with hsp70, which will cause increased protein aggregation and cell death by disinhibition of hsp70's anti-apoptotic function. It is believed that BAG-5 will play an important role in the mechanisms of neuronal death. BAG-5 may also be of interest due to its possible role as a modulator of the hsp70/hsp40 chaperone axis or its possible interaction and coordination of localization/ modulation of other BAG containing proteins via BAG-BAG heterodimerization.

Specifications

• Antigen: BAG5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BAG5
• Gene Alias: 1600025G07Rik; 4930405J06Rik; BAG cochaperone 5; BAG family molecular chaperone regulator 5; Bag5; BAG-5; BAG-family molecular chaperone regulator-5; BAG-family molecular chaperone regulator-5 (BAG-5); BCL2 associated athanogene 5; Bcl-2-associated athanogene 5; BCL2-associated athanogene 5; KIAA0873; LOC522854 protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 366734, 70369, 9529
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5QJC9, Q8CI32, Q9UL15
• Gene Symbols: BAG5
• Immunogen: A synthesized peptide derived from human BAG5(Accession Q9UL15), corresponding to amino acid residues L13-D63.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey
• Product Type: Antibody
• Isotype: IgG