BAIAP2 Mouse anti-Human, Clone: OTI 1D9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525560
DescriptionThe protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal domit neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|BAIAP2; BAP2; IRSP53; BAI1-associated protein 2; FLAF3; brain-specific angiogenesis inhibitor 1-associated protein 2; fas ligand-associated factor 3; insulin receptor substrate p53; insulin receptor substrate p53/p58|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of BAIAP2 produced in HEK293T cell|
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