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Baicalein, Tocris Bioscience™

Catalog Number 176150
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Quantity:
50 mg
This item is not returnable. View return policy
491-67-8
C15H10O5
270.24
MFCD00017459
FXNFHKRTJBSTCS-UHFFFAOYSA-N
baicalein, 5,6,7-trihydroxyflavone, noroxylin, 5,6,7-trihydroxy-2-phenyl-4h-chromen-4-one, biacalein, baicelein, chembl8260, 4h-1-benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl, 5,7-trihydroxyflavone, 5,6,7-trihydroxy-2-phenyl-chromen-4-one
5281605
CHEBI:2979
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
OC1=C(O)C(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1
This item is not returnable. View return policy
491-67-8
C15H10O5
270.24
MFCD00017459
FXNFHKRTJBSTCS-UHFFFAOYSA-N
baicalein, 5,6,7-trihydroxyflavone, noroxylin, 5,6,7-trihydroxy-2-phenyl-4h-chromen-4-one, biacalein, baicelein, chembl8260, 4h-1-benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl, 5,7-trihydroxyflavone, 5,6,7-trihydroxy-2-phenyl-chromen-4-one
5281605
CHEBI:2979
5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one
OC1=C(O)C(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1

Description

5- and 12-Lipoxygenase inhibitor

Inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 μM respectively). Also inhibits Raf-mediated MEK-1 phosphorylation in C6 rat glioma cells and induces G1 and G2 cell cycle arrest by decreasing cdk1, cdk2, cyclin D2 and cyclin A expression. Inhibits production of inflammatory cytokines by inhibiting NF-κB activation.
Quantity 50 mg
Formula Weight 270.24
Percent Purity >98%
Chemical Name or Material Baicalein

Safety and Handling

Recommended Storage Desiccate at -20°C
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