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BAM 7, Tocris Bioscience™

Catalog Number 481050
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
331244-89-4
C21H19N5O2S
405.476
KOCVKGYKBLJEPK-LYBHJNIJSA-N
5754137
(4E)-4-[(2-ethoxyphenyl)hydrazinylidene]-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazol-3-one
CCOC1=CC=CC=C1NN=C2C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C
This item is not returnable. View return policy
331244-89-4
C21H19N5O2S
405.476
KOCVKGYKBLJEPK-LYBHJNIJSA-N
5754137
(4E)-4-[(2-ethoxyphenyl)hydrazinylidene]-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazol-3-one
CCOC1=CC=CC=C1NN=C2C(=NN(C2=O)C3=NC(=CS3)C4=CC=CC=C4)C

Selective Bax activator; induces Bax-mediated apoptosis

Bax activator (EC50 = 3.3 μM); binds at the BH3-binding site. Selective for Bax over other antiapoptotic and proapoptotic proteins. Triggers Bax oligomerization in vitro; induces Bax-mediated apoptosis in mouse embryonic fibroblasts.
Quantity 50 mg
Synonym bam7, e-4-2-2-ethoxyphenyl hydrazono-3-methyl-1-4-phenylthiazol-2-yl-1h-pyrazol-5 4h-one, 3-methyl-1-4-phenyl-2-thiazolyl-1h-pyrazole-4,5-dione 4-2-2-ethoxyphenyl hydrazone, bam 7, bax activator molecule 7, 4-2-2-ethoxyphenyl hydrazono-3-methyl-1-4-phenylthiazol-2-yl-1h-pyrazol-5 4h-one, 4e-4-2-ethoxyphenyl hydrazinylidene-5-methyl-2-4-phenyl-1,3-thiazol-2-yl pyrazol-3-one, 4z-4-2-2-ethoxyphenyl hydrazin-1-ylidene-5-methyl-2-4-phenyl-1,3-thiazol-2-yl pyrazol-3-one, e-4-2-2-ethoxyphenyl hydrazono-5-methyl-2-4-phenylthiazol-2-yl-2,4-dihydro-3h-pyrazol-3-one
Formula Weight 405.47
Percent Purity >99%
Chemical Name or Material BAM 7
Recommended Storage Store at +4°C
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