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Bax Antibody (2D2), Alexa Fluor™ 532, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP233092AF532
Description
Bax Monoclonal specifically detects Bax in Human, Monkey, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.Specifications
Bax | |
Monoclonal | |
Alexa Fluor 532 | |
50 mM sodium borate with 0.05% sodium azide | |
BAX | |
A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein. (Uniprot: Q07812) | |
0.1 mL | |
Primary | |
Recognizes a protein of 21kDa, identified as the Bax protein. This monoclonal antibody is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2. | |
Store at 4°C in the dark. |
Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin) | |
2D2 | |
Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin | |
apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4 | |
Mouse | |
Protein A or G purified | |
Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors | |
581.0 | |
Human, Monkey, Mouse, Rat | |
IgG1 κ |
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