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Bax Mouse anti-Human, Monkey, Mouse, Rat, Alexa Fluor™ 750, Clone: 2D2, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233092AF750

Catalog No. NP233092A70


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Description

Description

Bax Monoclonal antibody specifically detects Bax in Human, Monkey, Mouse, Rat samples. It is validated for ELISA.
Specifications

Specifications

Bax
2D2
ELISA
Conjugated, Purified
BAX
A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Protein G purified
Apoptosis, Cancer, Core ESC Like Genes, Stem Cell Markers, Tumor Suppressors
Primary
581.0
Human, Monkey, Mouse, Rat
ELISA
Alexa Fluor™ 750
50 mM sodium borate with 0.05% sodium azide
apoptosis regulator BAX, BCL2-associated X protein, Bcl2-L-4, BCL2L4bcl2-L-4, Bcl-2-like protein 4
Mouse
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
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