Tocris Bazedoxifene acetate
Potent and selective estrogen receptor modulator (SERM)
Manufacturer: Tocris 5263/10
DescriptionPotent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99nM for ERα and ERβ respectively). Inhibits 17β-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium.
- Chemical Name: 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate
- Formula: C30H34N2O3.C2H4O2
- CAS Number: 198481-33-3
- Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
- Purity: >98
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