Tocris™ Bazedoxifene acetate

Potent and selective estrogen receptor modulator (SERM)

Manufacturer: Tocris™ 5263/10

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Catalog No. 52-631-0

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Disclaimers:

For Research Use Only


    Specifications

    Product Type Bazedoxifene acetate
    Inhibitors Bazedoxifene acetate
    Purity >98
    Molecular Weight 530.65
    Quantity 10mg

    Potent selective estrogen receptor modulator (SERM) (IC50 values are 26 and 99nM for ERα and ERβ respectively). Inhibits 17β-estradiol-induced proliferation in MCF-7 cells. Co-treatment with Raloxifene (Cat No. 2280) completely abolishes raloxifene-induced stimulation of luminal epithelial cells and myometrium.

    • Chemical Name: 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol acetate
    • Formula: C30H34N2O3.C2H4O2
    • CAS Number: 198481-33-3
    • Solubility: Soluble to 100mM in DMSO and to 20mM in ethanol
    • Purity: >98

  • Description & Specifications

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