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Bcl-10 Mouse anti-Human, Alexa Fluor™ 350, Clone: BL10/411, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP233190AF350

Catalog No. NP233190A30


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Description

Description

Bcl-10 Monoclonal antibody specifically detects Bcl-10 in Human samples. It is validated for ELISA.
Specifications

Specifications

Bcl-10
BL10/411
ELISA
Conjugated, Purified
BCL10
Human BCL10 recombinant protein (epitope aa122-168)
Protein G purified
Apoptosis, Cancer
Primary
8915.0
Human
ELISA
Alexa Fluor™ 350
50 mM sodium borate with 0.05% sodium azide
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Mouse
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
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