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Bcl-2 Antibody (BCL2/2210R), Alexa Fluor™ 488, Novus Biologicals™
SDP

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP275764AF488

Catalog No. NB008985


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Description

Description

Bcl-2 Monoclonal specifically detects Bcl-2 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Specifications

Specifications

Bcl-2
Monoclonal
Alexa Fluor 488
50mM Sodium Borate with 0.05% Sodium Azide
BCL2
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
0.1 mL
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Store at 4°C in the dark.
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
BCL2/2210R
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Rabbit
Protein A or G purified
RUO
Primary
Human
IgG
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