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Bcl-2, Rabbit anti-Human, Alexa Fluor 532, Clone: BCL2/2210R, Novus Biologicals™

Rabbit Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275764AF532

Catalog No. NB008986


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Description

Description

Bcl-2 Monoclonal antibody specifically detects Bcl-2 in Human samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin).
Specifications

Specifications

Bcl-2
BCL2/2210R
Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
50mM Sodium Borate with 0.05% Sodium Azide
BCL2
Recombinant full-length human Bcl-2 protein
Monoclonal
Protein A or G purified
RUO
Store at 4°C in the dark.
This antibody recognizes a protein of 25-26 kDa, identified as the bcl-2 oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Western Blot,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin)
Alexa Fluor 532
Purified,Conjugated
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Rabbit
IgG
Primary
0.1 mL
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors
Human
SDS
Documents
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