Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Bcl-6, Mouse anti-Human, Alexa Fluor 532, Clone: BCL6/1982, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275749AF532

Catalog No. NB008815


Add to cart

Description

Description

Bcl-6 Monoclonal antibody specifically detects Bcl-6 in Human samples. It is validated for ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin).
Specifications

Specifications

Bcl-6
BCL6/1982
ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin
50mM Sodium Borate with 0.05% Sodium Azide
BCL6
Recombinant human Bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary)
Monoclonal
Protein A or G purified
RUO
Store at 4°C in the dark.
Recognizes a protein of 95 kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
ELISA,Immunohistochemistry,Immunohistochemistry (Paraffin)
Alexa Fluor 532
Purified,Conjugated
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Mouse
IgG1 Kappa
Primary
0.1 mL
Cancer, Cell Cycle and Replication, Tumor Suppressors
Human
SDS
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit