Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Bcl-G Mouse anti-Human, Clone: OTI6D1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527070

Catalog No. PIMA527070


Add to cart

Description

Description

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predomitly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.
Specifications

Specifications

Bcl-G
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9BZR8
BCLG; apoptosis facilitator Bcl-2-like protein 14; apoptosis regulator BCL-G; bcl2-L-14
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79370
Immunohistochemistry (Paraffin), Western Blot
OTI6D1
Unconjugated
BCL2L14
Liquid
BCL2L14
Human recombit protein fragment corresponding to amino acids 116-216 of BCL2L14 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit