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BCL2L1 Mouse anti-Human, Clone: OTI2D1, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA506188

Catalog No. 50-167-6528


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Description

Description

The protein encoded the BCL-X gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Specifications

Specifications

BCL2L1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q07817
BCL-XL/S, BCL2L, BCLX, Bcl-X, PPP1R52
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
598
Immunohistochemistry (Paraffin), Western Blot
OTI2D1
Unconjugated
BCL2L1
Liquid
BCL2L1
Full length human recombit protein of human BCL2L1 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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