BCL2L10 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 181141AP
DescriptionThe protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|Anti apoptotic protein NrH, Apoptosis regulator Bcl B, BCL2L10, Boo, Diva|
|Immunohistochemistry (Paraffin), Western Blot|
|BCL2L10 Fusion Protein Ag12596|
|Antigen Affinity Chromatography|
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