BCoR Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301673A

Catalog No. 50-156-0968

Description

The recommended shelf life for this product is 1 year from date of receipt.

Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 ′Lys-4′ (H3K4me3) and ′Lys-36′ (H3K36me2). {ECO:0000269; PubMed:10898795, ECO:0000269; PubMed:15004558, ECO:0000269; PubMed:18280243, ECO:0000269; PubMed:19578371, ECO:0000269; PubMed:23911289}.

Specifications

• Antigen: BCoR
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BCOR
• Gene Alias: ANOP2, MAA2, MCOPS2, BCL-6 corepressor, BCL-6 interacting corepressor, BCL6 co-repressor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54880
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/ml
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: Q6W2J9
• Gene Symbols: BCOR
• Immunogen: Between 1705 and 1755
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG