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BCR Rabbit anti-Human, Non-human primate, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 225851AP

Catalog No. 50-173-3895


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Description

Description

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

BCR
0.45 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P11274
ALL, BCR, breakpoint cluster region, CML, D22S11, D22S662, PHL
Rabbit
IgG
150 μL
-20°C
Primary
613
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation
Unconjugated
BCR
Liquid
BCR
BCR Fusion Protein Ag18281
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Non-human primate
Documents
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