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Alfa Aesar™ Benzenesulfonamide, 98+%

Manufacturer:  Alfa Aesar™ A108910I

Quantity 5000g

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Catalog No. AAA108910I


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Specifications

Description

Applications
The presence of the benzenesulfonylamido (BS) groups shifted the activity of classic antimicrobial fluoroquinolones from being more active against Gram-negative to Gram-positive strains. Biospecific adsorption of carbonic anhydrase to self-assembled monolayers of alkanethiolates that present benzenesulfonamide groups on gold. Biospecific binding of carbonic anhydrase to mixed sams presenting benzenesulfonamide ligands led to a model system for studying lateral steric effects. In engineering the specificity of antibacterial fluoroquinolones, benzenesulfonamide modifications at c-7 of ciprofloxacin change its primary target instreptococcus pneumoniae from topoisomerase iv to gyrase. Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors.

Solubility
Soluble in methanol (25 mg/ml), and water (4.3 mg/ml at 16°C).

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Description & Specifications

Chemical Identifiers

98-10-2
157.19
1100566
C6H7NO2S
MFCD00007930
Benzenesulfonamide

Specifications

98-10-2
157.19
1100566
5000g
Odorless
≥98%
C6H7NO2S
MFCD00007930
151° to 154°C
250°C (482°F)
Benzenesulfonamide

Safety and Handling

SDS & Safety Documents

GHS H Statement
H302
Harmful if swallowed.

GHS P Statement
P280f
Wear protective clothing.

Warning

RTECSNumber : DA9380000

TSCA : TSCA

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