Benzyl 2,2,2-trichloroacetimidate, 98%, Thermo Scientific Chemicals

Description

Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups. It acts as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It can also be used for mild esterification of carboxylic acids in the presence of a catalytic amount of BF₃ etherate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups. It acts as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It can also be used for mild esterification of carboxylic acids in the presence of a catalytic amount of BF₃ etherate.

Solubility
Miscible with cyclohexane/dichloromethane.

Notes
Moisture and light sensitive. Incompatible with strong oxidizing agents and strong acids.

Specifications

• Density: 1.356
• Boiling Point: 110°C to 114°C (0.5 mmHg)
• Flash Point: >110°C (230°F)
• Refractive Index: 1.545
• Quantity: 50 g
• Beilstein: 2525375
• Sensitivity: Moisture sensitive
• Synonym: benzyl 2,2,2-trichloroacetimidate, benzyl trichloroacetimidate, benzyltrichloroacetimidate, trichloroacetimidic acid benzyl ester, 2,2,2-trichloro-1-phenylmethoxy ethanimine, ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester, benzyl 2,2,2-trichloroethanecarboximidate, benzyl2,2,2-trichloroacetimidate, acmc-209pmn, benzyl trichloracetimidate
• Solubility Information: Miscible with cyclohexane/dichloromethane.
• Formula Weight: 252.53
• Percent Purity: 98%
• Chemical Name or Material: Benzyl 2,2,2-trichloroacetimidate

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	617-271-1
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only