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Bestrophin-1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 219101AP

Catalog No. 50-173-3635


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Description

Description

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.
Specifications

Specifications

Bestrophin-1
0.51 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O76090
ARB, BEST, BEST1, bestrophin 1, Bestrophin-1, BMD, TU15B, VMD2
Rabbit
IgG
150 μL
-20°C
Primary
7439
Western Blot
Unconjugated
BEST1
Liquid
BEST1
Bestrophin-1 Fusion Protein Ag15129
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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