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Alfa Aesar™ beta-Estradiol, 99% (dry wt.), ca 3% water

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Quantity:
1g
5g
25g
50-28-2
C18H24O2
272.388
MFCD00003693
VOXZDWNPVJITMN-ZBRFXRBCSA-N
estradiol,beta-estradiol,17beta-estradiol,oestradiol,dihydrofolliculin,estrace,ovocyclin,progynon,dihydrotheelin,dihydroxyestrin
5757
CHEBI:16469
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
50-28-2
C18H24O2
272.388
MFCD00003693
VOXZDWNPVJITMN-ZBRFXRBCSA-N
estradiol,beta-estradiol,17beta-estradiol,oestradiol,dihydrofolliculin,estrace,ovocyclin,progynon,dihydrotheelin,dihydroxyestrin
5757
CHEBI:16469
(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
Applications
β-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating female puberty induction, as in the treatment of delayed puberty caused by hypogonadism or Turner′s syndrome. In addition to this, it is used as part of the hormone replacement therapy for transgender women.

Solubility
Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.

Notes
Incompatible with strong oxidizing agents.
Optical Rotation +79° (c=1 in Dioxane)
Quantity 1g
Melting Point 175°C to 178°C
Beilstein 1914275
Merck Index 14,3703
Solubility Information Soluble in dimethyl sulfoxide,ethanol ,water,phosphate buffer saline,dimethyl formamide,acetone,dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Formula Weight 272.39
Percent Purity 99%
Chemical Name or Material beta-Estradiol
Assay (dry wt.), ≈3% water

GHS H Statement
H350-H360
May cause cancer.
May damage fertility or the unborn child.

P201-P202-P260-P263-P264b-P270-P271-P281-P304+P340-P308+P313-P501c

H350-H361fd-H362-H373

EINECSNumber : 200-023-8

RTECSNumber : KG2975000

TSCA : No

Recommended Storage : Ambient temperatures