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Invitrogen™ beta Synuclein Polyclonal Antibody
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Catalog No. 01670514
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100 μg
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Catalog No. Quantity
01-670-514 100 μg
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Catalog No. 01-670-514 Supplier Invitrogen™ Supplier No. PA118261
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Description

Sheep Polyclonal Antibody

Reconstitute in 100 μL of sterile water. Centrifuge to remove any insoluble material. After reconstitution keep aliquots at -20 °C for a higher stability, and at 4 °C with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.

Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.
TRUSTED_SUSTAINABILITY

Specifications

Antigen beta Synuclein
Applications Immunohistochemistry (Frozen)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SNCB
Gene Accession No. Q16143, Q63754
Gene Alias AI838531; betaSYN; beta-synuclein; Phosphoneuroprotein 14; PNP 14; Sncb; synuclein beta; synuclein, beta
Gene Symbols SNCB
Host Species Sheep
Immunogen Synthetic peptide corresponding to residues I(108) E P L M E P E G S Y E D P P Q E(125) of human beta synuclein protein.
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 113893, 6620
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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