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MilliporeSigma™ Supelco™ BIOshell™ A400 Protein C18 Column, 3.4 μm Particle Size (Dia. 1-4.6 mm)

BIOshell™ 400 Å Protein C18 columns contain 3.4 μm advanced Fused-Core™ particles with 400 Å pores that are specifically engineered to provide efficient separation of larger proteins.

Manufacturer:  MilliporeSigma™ Supelco™ 67478U

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Catalog No. 11-100-7995

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BIOshell™ 400 Å Protein C18 columns offer maximum hydrophobicity for resolving tricky hydrophilic and PEGylated proteins. The 3.4 μm Fused-Core particles allow a shorter analysis time yet similar back pressure to fully porous 1.7 μm, 300 Å fully porous C18 particles. These columns can be operated long term at pressures up to 9000 psi (600 bar), temperatures up to 90°C, and within the pH range of 1 to 9.


4.6 mm
3.4 μm
̃15 m2/g
Stainless Steel
2 cm
1 to 9
C18 (octadecyl)
C18 (octadecyl) Phase/Spherical Silica Particle Platform
Reversed Phase
Fused-Core HPLC
Product Certifications


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BIOshell is a trademark of Sigma-Aldrich Co. LLC