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Echelon Biosciences Research LabsSupplier Diversity Partner Biotin Phosphatidylinositol 3-phosphate 10 ug  DFS Item

Manufacturer:  Echelon Biosciences Research LabsSupplier Diversity Partner C03B610UG

Biotin Phosphatidylinositol 3-phosphate is a water soluble analog of PI(3)P labeled with biotin at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate (PI(3)P) is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Catalog No. 50-720-041



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