BIRC7 Mouse anti-Human, Clone: 88C570, Abnova™
Mouse monoclonal antibody raised against recombinant human BIRC7.
Manufacturer: Abnova Corporation MAB12961
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq]
|Mouse monoclonal antibody raised against recombinant human BIRC7.|
|In PBS (0.05% BSA, 0.05% sodium azide).|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot (1-2 ug/mL) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human BIRC7.|
|Protein G purification|
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