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Blasticidin S hydrochloride, 10 mg/mL in HEPES buffer, sterile-filtered, Alfa Aesar™

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Quantity:
1mL
5 x 1mL
3513-03-9
C17H27ClN8O5
458.90
MFCD02091640
YQXYQOXRCNEATG-UHFFFAOYNA-N
124080960
(2R,3S,6S)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride
CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
3513-03-9
C17H27ClN8O5
458.90
MFCD02091640
YQXYQOXRCNEATG-UHFFFAOYNA-N
124080960
(2R,3S,6S)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride
CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
Applications
Blasticidin S hydrochloride, acts quickly by inhibiting peptide bond formation by the ribosome. The blasticidin S resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative. Blasticidin S is used for the prevention of contamination of cell cultures.

Solubility
Soluble in water. Insoluble in organic solvents.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
Physical Form Liquid
Concentration 10mg/mL in HEPES buffer
Quantity 5 x 1mL
Chemical Name or Material Blasticidin S hydrochloride, sterile-filtered

GHS H Statement
H302
Harmful if swallowed.

GHS P Statement
P264-P270-P301+P312-P330-P501a
Wash thoroughly after handling.
Do not eat, drink or smoke when using this product.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth.
Dispose of contents/container in accordance with local/regional/national/international regulations.

Warning

storageNote1 : −30° to −10°C