Invitrogen™ BLOC1S3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106958

Catalog No. PIPA5106958

Description

Sequence homology: Cow: 93%; Dog: 86%; Goat: 79%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Mouse: 100%; Rat: 100%; Sheep: 79%; Zebrafish: 79%.

Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.

Specifications

• Antigen: BLOC1S3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: BLOC1S3
• Gene Alias: biogenesis of lysosomal organelles complex 1 subunit 3; biogenesis of lysosomal organelles complex-1, subunit 3; biogenesis of lysosome-related organelles complex 1 subunit 3; biogenesis of lysosome-related organelles complex-1, subunit 3; BLOC-1 subunit 3; BLOC1S3; BLOS3; HPS8; reduced pigmentation, mouse, homolog of; RP
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 388552
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q6QNY0
• Gene Symbols: BLOC1S3
• Immunogen: Synthetic peptide located within the following region: RGRPTGLRVA GEAAETDSEP EPEPEPTAAP RDLPPLVVQR ESAEEAWGTE.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov