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Blood Group Antigen H (O) Type 1 Mouse anti-Human, Clone: 17-206, eBioscience™ Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

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Catalog No. 14-981-095



Description

Description

The MAb 17-206 recognizes the human blood group antigen H (O) type 1, a subtype primarily found in epithelial and secretory cells. The precursor H antigen is modified by addition of saccharides to carbohydrate chains of proteins and lipids on erythrocytes and epithelial cells. The type, attachment, location, and sequence of saccharides determines the blood group antigen subtype and is mediated by multiple glycosyl transferases. Depending on ABO blood type, the H antigen is converted into either the A antigen, B antigen, both the A and B antigen, or left unconverted (O antigen). Evidence that the blood group antigen H is not expressed in tumor cells and that the level correlates with disease progression suggests that the blood group antigen H may be involved in cell proliferation, cell adhesion, and angiogenesis, although its exact function remains to be determined. The 17-206 antibody does not recognize blood group antigen H (O) type 2.

Blood Group Antigen H (O) Type 1 Monoclonal antibody specifically detects Blood Group Antigen H (O) Type 1 in Human samples. It is validated for ELISA, Immunohistochemistry (Paraffin)
Specifications

Specifications

Blood Group Antigen H (O) Type 1
ELISA, Immunohistochemistry (Paraffin)
17-206
Unconjugated
ABH; BG-H; BG-H1; group h
IgG3
10 mg
4° C
Primary
Human
Liquid
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
SDS
Documents
Product Certifications
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