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  7. BMS 182874 hydrochloride, Tocris Bioscience™

BMS 182874 hydrochloride, Tocris Bioscience™

Catalog Number 144150
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
1215703-04-0
C17H20ClN3O3S
381.875
UZZFRNZGYDOBAO-UHFFFAOYSA-N
bms 182874 hydrochloride, 5-dimethylamino-n-3,4-dimethyl-5-isoxazolyl-1-naphthalenesulfonamide hydrochloride
56972163
5-(dimethylamino)-N-(3,4-dimethyl-1,2-oxazol-5-yl)naphthalene-1-sulfonamide;hydrochloride
CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC3=C2C=CC=C3N(C)C.Cl
This item is not returnable. View return policy
1215703-04-0
C17H20ClN3O3S
381.875
UZZFRNZGYDOBAO-UHFFFAOYSA-N
bms 182874 hydrochloride, 5-dimethylamino-n-3,4-dimethyl-5-isoxazolyl-1-naphthalenesulfonamide hydrochloride
56972163
5-(dimethylamino)-N-(3,4-dimethyl-1,2-oxazol-5-yl)naphthalene-1-sulfonamide;hydrochloride
CC1=C(ON=C1C)NS(=O)(=O)C2=CC=CC3=C2C=CC=C3N(C)C.Cl

Description

Highly selective, orally active non-peptide ETA antagonist

Potent, selective and competitive non-peptide endothelin ETA receptor antagonist (Ki = 48 nM). Displays > 1000-fold selectivity over ETB receptors. Inhibits ET-1-induced pressor response following oral or intravenous administration in vivo. Inhibits ET-1-induced longitudinal muscle contraction in the mouse colon in vitro.
Quantity 50 mg
Formula Weight 381.88
Percent Purity >98%
Chemical Name or Material BMS 182874 hydrochloride

Safety and Handling

Recommended Storage Store at Room Temperature
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