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Tocris™ BMS 195614

Selective RARalpha antagonist

Manufacturer:  Tocris™ 3660/50

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Catalog No. 36-605-0R


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Disclaimers:

For Research Use Only


Specifications

Description

Neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5nM). Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. Antagonizes agonist-induced coactivator (CoA) recruitment.
  • Chemical Name: 4-[[[5,6-Dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoic acid
  • Formula: C29H24N2O3
  • CAS Number: 253310-42-8
  • Solubility: Soluble to 25mM in DMSO
  • Purity: >98
Description & Specifications

Specifications

BMS 195614
>98
50mg
BMS 195614
448.51
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