Tocris™ BMS 195614

Selective RARalpha antagonist

Manufacturer: Tocris™ 3660/50

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Catalog No. 36-605-0R

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For Research Use Only


    Product Type BMS 195614
    Inhibitors BMS 195614
    Purity >98
    Molecular Weight 448.51
    Quantity 50mg

    Neutral retinoic acid receptor (RAR) α-selective antagonist (Ki = 2.5nM). Displays no significant effect on nuclear receptor corepressor (NCoR) binding; moderately decreases SMRT binding to RAR. Antagonizes agonist-induced coactivator (CoA) recruitment.

    • Chemical Name: 4-[[[5,6-Dihydro-5,5-dimethyl-8-(3-quinolinyl)-2-naphthalenyl]carbonyl]amino]benzoic acid
    • Formula: C29H24N2O3
    • CAS Number: 253310-42-8
    • Solubility: Soluble to 25mM in DMSO
    • Purity: >98

  • Description & Specifications

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