Tocris™ BMS 309403

Potent and selective FABP4 inhibitor

Manufacturer: Tocris™ 5258/10

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Catalog No. 52-581-0

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For Research Use Only


    Specifications

    Product Type BMS 309403
    Inhibitors BMS 309403
    Purity >98
    Molecular Weight 474.55
    Quantity 10mg

    Potent and selective fatty acid binding protein 4, adipocyte (FABP4) inhibitor (Ki values are <2, 250 and 350nM for FABP4, FABP3 and FABP5 respectively). Decreases fatty acid uptake in adipocytes in vitro and reduces atherosclerotic lesion area in a mouse model of atherosclerosis. Reduces blood glucose levels and increases insulin sensitivity in a mouse model of obesity. Orally active.

    • Chemical Name: 2-[[2'-(5-Ethyl-3,4-diphenyl-1H-pyrazol-1-yl)[1,1'-biphenyl]-3-yl]oxy]-acetic acid
    • Formula: C31H26N2O3
    • CAS Number: 300657-03-8
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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