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Tocris Bioscience™ BMS 345541

Name: Tocris Bioscience&trade; BMS 345541
Brand: Tocris Bioscience&trade;
SKU: 48-065-0
Price: 1599.64 USD

Selective allosteric inhibitor of IKK; anti-inflammatory

Supplier: Tocris Bioscience™ 4806/50

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Catalog No. 48-065-0

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Description

BMS 345541 is a selective allosteric inhibitor of IKK (IC50 values are 0.3 and 4.0 μM for IKKβ and IKKα respectively). Exhibits no effect against a panel of 15 other kinases. Attenuates LPS-induced cytokine production in vitro and blocks NFκB dependent transcription in mice. Also suppresses joint destruction in a mouse model of arthritis.

Specifications

Purity	>99%
Product Type	BMS 345541
Inhibitors	BMS 345541

Quantity	50 mg
Molecular Weight (g/mol)	291.78

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Tocris Bioscience™ BMS 345541

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